Measurement of folding in surfaces of arbitrary size in human brain development

Claudia Rodriguez-Carranza 1 P. Mukherjee 2 Dan Vigneron 2 James Barkovich 2 C. Studholme 1, 2
1 NCIRE - Northern California Institute for Research and Education [San Francisco]
2 Department of Radiology [San Francisco]
Abstract : This paper describes a novel approach to in-vivo measurement of brain surface folding in clinically acquired neonatal MR image data. Specifically it addresses the problem of comparing folding of surfaces of arbitrary area. Most of the current measures of folding are not independent of the area of the surface from which they are derived. Therefore, applying them to whole brains or subregions of different sizes result in differences which may or may not reflect true differences in folding. In this paper we describe alternative approaches to deriving area independent measures. The measures were applied to twelve premature infants (age 28-37 weeks) from which cortical gray and white surfaces were extracted. Experimental results show that previous folding measures are sensitive to the size of the surface patch, and that the area independent measures proposed here provide significant improvements. Such a system provides a tool to allow the study of structural development in the neonatal brain within specific functional subregions, which may be critical in identifying later neurological impairment.
Type de document :
Communication dans un congrès
Xavier Pennec and Sarang Joshi. 1st MICCAI Workshop on Mathematical Foundations of Computational Anatomy: Geometrical, Statistical and Registration Methods for Modeling Biological Shape Variability, Oct 2006, Copenhagen, Denmark. pp.164-173, 2006
Liste complète des métadonnées

Littérature citée [20 références]  Voir  Masquer  Télécharger
https://hal.inria.fr/inria-00636326
Contributeur : Service Ist Inria Sophia Antipolis-Méditerranée / I3s <>
Soumis le : jeudi 27 octobre 2011 - 11:52:04
Dernière modification le : samedi 25 novembre 2017 - 14:06:40
Document(s) archivé(s) le : lundi 5 décembre 2016 - 00:23:07

Fichier

Rodriguez-Carranza_MFCA06.pdf
Fichiers produits par l'(les) auteur(s)

Identifiants

  • HAL Id : inria-00636326, version 1

Collections

MFCA | MFCA06

Citation

Claudia Rodriguez-Carranza, P. Mukherjee, Dan Vigneron, James Barkovich, C. Studholme. Measurement of folding in surfaces of arbitrary size in human brain development. Xavier Pennec and Sarang Joshi. 1st MICCAI Workshop on Mathematical Foundations of Computational Anatomy: Geometrical, Statistical and Registration Methods for Modeling Biological Shape Variability, Oct 2006, Copenhagen, Denmark. pp.164-173, 2006. 〈inria-00636326〉

Exporter

BibTeX TEI DC DCterms EndNote

Partager

Métriques

Consultations de la notice

145

Téléchargements de fichiers

132

Contact


archive-ouverte@inria.fr