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Inter-operative biopsy site relocalization in gastroscopy : application to oesophagus

Anant Suraj Vemuri 1
1 ASCLEPIOS - Analysis and Simulation of Biomedical Images
CRISAM - Inria Sophia Antipolis - Méditerranée
Abstract : Gastrointestinal (GI) procedures, specifically, oesophageal interventions involve periodic monitoring or surveillance of the internal anatomy, which involve obtaining biopsies at different regions along the oesophagus. The tracking and relocalization of these biopsy sites ``inter-operatively'' poses a significant challenge for providing targeted treatments. This thesis, clarifies the concept of relocalization, and analyses the need for a platform to aide GI endoscopy. Based on the understanding of the clinical context in oesophageal procedures; a novel framework to use electromagnetic tracking system is proposed, which is used to perform a ``recording'' of an intervention. This framework and the recording is then used to provide a guided navigation to the GI expert, during a follow-up surveillance endoscopy; for accurate re-positioning of the endoscope at previously targeted sites. This is achieved using inter-operative video synchronization, and the various steps involved in achieving this are described in this thesis. A careful analysis of noise affecting the system is performed, to propose quantitative analysis using synthetic and realdata collected on pigs. A set of qualitative experiments were also proposed using 10 experts to indicate benefit to the GI community. The quantitative experiment indicated that the relocalization was achieved with an accuracy of 10mm, and the qualitative experiments showed that the biopsy site relocalization rate improved from 47.5% to 94%. The thesis then proceeds to provide two additional improvements using additional information collected during the GI intervention for a complete solution
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Anant Suraj Vemuri. Inter-operative biopsy site relocalization in gastroscopy : application to oesophagus. Other [cs.OH]. Université Nice Sophia Antipolis, 2016. English. ⟨NNT : 2016NICE4018⟩. ⟨tel-01310047v3⟩

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