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URL : https://hal.archives-ouvertes.fr/hal-01259233
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, Amphotericin primarily kills yeast by simply binding ergosterol, Proceedings of the National Academy of Sciences of the United States of America, vol.109, issue.7, pp.2234-2243, 2012.
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, Amphotericin B nano-aggregates circumvent toxicity constraints and treat systemic fungal infection in experimental animals, Scientific Reports, vol.7, 2017.
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Tuning complement activation and pathway through controlled molecular architecture of dextran chains in nanoparticle corona, International Journal of Pharmaceutics, vol.532, issue.2, pp.769-78, 2017. ,
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, Alternative mechanism for amphotericin B uptake by macrophage cell-like: the possible role of the complement immune system, 2016.
AmB loading into micro-and nano-emulsion systems. Unpublished work, 2017. ,
Development and characterization of a microemulsion system containing amphotericin B with potential ocular applications, Current Drug Delivery, vol.13, issue.6, pp.982-93, 2016. ,
In vitro and in vivo antileishmanial activity of cheap amphotericin B formulations: heated amphotericin B and amphotericin B-loaded microemulsion, 2017. ,
Microemulsion encapsulation of an AmB soluble derivative ,
,
, Amphotericin forms an extramembranous and fungicidal sterol sponge, Nature Chemical Biology, vol.10, issue.5, pp.400-121, 2014.
,
, Amphotericin primarily kills yeast by simply binding ergosterol, Proceedings of the National Academy of Sciences of the United States of America, vol.109, issue.7, pp.2234-2243, 2012.
Pharmaceutical strategies for amphotericin B delivery, 2017. ,
Amphotericin B-containing sodium deoxycholate micellar systems: a comparison of physicochemical characteristics of marketed products, 2017. ,
NanoDisk containing super aggregated amphotericin B: a high therapeutic index antifungal formulation with enhanced potency, International Journal of Nanomedicine, vol.8, pp.4733-4775, 2013. ,
,
, Amphotericin B nano-aggregates circumvent toxicity constraints and treat systemic fungal infection in experimental animals, Scientific Reports, vol.7, 2017.
Amphotericin B super-aggregates: formation and influence on the drug stability, 2017. ,
,
, Alternative mechanism for amphotericin B uptake by macrophage cell-like: the possible role of the complement immune system, 2016.
AmB loading into micro-and nano-emulsion systems. Unpublished work, p.175, 2017. ,
Development and characterization of a microemulsion system containing amphotericin B with potential ocular applications, Current Drug Delivery, vol.13, issue.6, pp.982-93, 2016. ,
In vitro and in vivo antileishmanial activity of cheap amphotericin B formulations: heated amphotericin B and amphotericin B-loaded microemulsion, 2017. ,
Microemulsion encapsulation of an AmB soluble derivative ,
Emulsion systems as a carrier for oral delivery of amphotericin B, 14èmes Journées de l'École Doctorale Innovation Thérapeutiquque, 2014. ,
Evaluation of the aggregation state of amphotericin B loaded in nanoemulsions intended for oral delivery, Therapeutic Possibilities, technological ChallengesAbstract Book, pp.314-316, 2014. ,
New formulations of amphotericin B to improve its therapeutic index for leishmaniasis treatment, COST Action CM1307 2nd Conference, p.27, 2015. ,
Incorporação de anfotericina B em um sistema emulsionado: influência da concentração do fármaco em seu estado de agregação, XVII Congresso Científico e XVI Mostra de Extensão da ,
, Construção do Futuro. Natal, 2015.
Nanossistema de anfotericina B para via oral: avaliação do estado de agregação do fármaco em meios siimulados, XVII Congresso Científico e XVI Mostra de Extensão da UnP, 2015. ,
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Is a liposomal system able to form amphotericin B super-aggregates, 11th International Congress, vol.178 ,
, Ribeirão Preto. Pharmaceutical sciences in an emerging economy: Challenges for a sustainable world, 2017.
, D studies, my mentor and I presented to the RENORBIO a project in biotechnology entitled "Cationic nanoemulsions for gene delivery: intracellular process and in vitro/in vivo evaluation of gene expression", a natural continuation of the work developed for my master degree, in which we have developed a cationic system able to pack a plasmid DNA, clarifying the physical factors influencing the genetic material compaction into a pharmaceutical system, Stearylamine-containing cationic nanoemulsions as a promising carrier for gene delivery In 2013, when I have started my Ph
Although in a short period of time (around four months), summed to some results from the master period, the previous Ph.D project resulted in paper entitled "Stearylamine-Containing Cationic Nanoemulsion as a Promising Carrier to Gene Delivery ,
, Short Curriculum vitae 182 PERSONAL INFORMATION Name: André Leandro Silva Date birth, pp.14-23
Address: Rua 21 de Setembro, p.41 ,
, , vol.47, pp.806-810
, andre_leandro@outlook.com.br or andre.leandro@ufob.edu.br FORMAL EDUCATION 2006 -2010 Bachelor in Pharmacy Universidade Potiguar
, Scholarship: Programa Universidade para Todos (ProUni), pp.2011-2013
, Capes 2013 -2017 PhD in Biotechnology / Biopharmacie et Pharmacotechnie
, Recanto dos Pássaros. UFOB -Campus Reitor Edgard Santos Centro das Ciências Biológicas e da Saúde Curso, vol.316, 2017.
,
, PhD Student
, , 2010.
, Pague Menos Drugstore 2010 -2013 Pharmacist LANGUAGE SKILLS 1. Portuguese: Native 2. Spanish: Fluent 3. French: Advanced 4. English: Advanced LIST OF PUBLICATIONS
Stearylamine-containing cationic nanoemulsion as a promising carrier for gene delivery, Journal of Nanoscience and Nanotechnology (Print), vol.16, pp.1339-1384, 2016. ,
,
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Development and characterization of a microemulsion system containing amphotericin B with potential ocular applications, Current Drug Delivery, vol.13, issue.6, pp.982-93, 2016. ,
,
Physical factors affecting plasmid DNA compaction in stearylamine-containing nanoemulsions intended for gene delivery, Pharmaceuticals, vol.5, pp.643-54, 2012. ,
Comparação dos métodos hospitalar e domiciliar de fracionamento de comprimidos de Furosemida 40mg, Catussaba, vol.1, pp.31-40, 2011. ,
, The full CV can be