. .. Méthodes, 171 7.2.1 Méthodes de mise en correspondance au niveau schéma

. .. Méthodes,

. .. Schéma-global,

. .. Wordnet,

.. .. Conclusion,

A. .. De, 178 7.4.1 Amélioration du processus de requêtes
URL : https://hal.archives-ouvertes.fr/hal-00763846

. .. Processus-de-requêtes,

, domaine biomédical au sein des définitions et utilise plusieurs domaines concernant

, Il serait intéressant d'intégrer EuroWordNetà notre travail. C'est une base de données multilingue crééeà partir de WordNets de nombreux pays européens (italien, français, espagnol, etc, vol.98

, Pour déterminer une des paires (concept, synset) comme meilleure, il faudrait comparer non plus uniquement les définitions et le nombre de synonymes communs de langue anglaise mais aussi ceux des autres langues. Par exemple, le terme Reason en anglais est associéà deux concepts UMLS : Reason for (C0392360) et Reasonning (C0684328) età six synsets WordNet, En plus d'être structurée de la même manière que WordNet, cette ressource permet d'interconnecter les langues pour pouvoir passer de mots dans une langue aux mots similaires dans n'importe quelle autre langue

, UMLS et WordNet présente des avantages et des inconvénients et le fait de combiner ces deux ressources compense souvent les problèmes posés par l'un au travers des bénéfices apportés par l'autre. L'UMLS est disponible gratuitementà condition de disposer d'une licence. Pour notre travail, nous avons récupéré en local l'UMLS et WordNet (qui est libre d'accès) afin de pouvoir faire toutes les recherches et manipulations dont nous avions besoin

L. , En ce qui concerne l'UMLS, il faut tout d'abord enéliminer les cycles. Puis, pour l'UMLS comme pour WordNet, il faut recommencer la phase de mises en correspondance des EDs avec les concepts et synsets respectivement. Pour les résultats identiques, aucune modification n'est requise, en revanche si un concept ou un synset ontété supprimés ou modifiés

, Apport de méthodes formelles pour le schéma global

, Le schéma global de notre système est bien formé structurellement puisqu'il est construit sous la forme d'un graphe orienté sans cycle mais n'est pas formel. Kashyap a décrit une méthode pour représenter l'ensemble du Réseau Sémantique au format OWL (relations et types sémantiques) [Kashyap 03] mais cela n'est pas suffisant pour nos besoins

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, Conférences internationales avec comité de lecture et publication des actes

F. Mougin, A. Burgun, and O. Bodenreider, Using WordNet to Improve the Mapping of Data Elements to UMLS for Data Sources Integration, AMIA Annu Symp Proc, pp.574-578, 2006.

F. Mougin, A. Burgun, and O. Bodenreider, Data integration through data elements : Mapping data elements to terminological resources, Proceedings of the Second International Symposium on Semantic Mining in Biomedicine (SMBM-2006), pp.52-59, 2006.

I. Alecu, C. Bousquet, F. Mougin, and M. C. Jaulent, Mapping of the WHO-ART terminology on

, Snomed CT to improve grouping of related adverse drug reactions. Stud Health Technol Inform, vol.124, pp.833-838, 2006.

N. Garcelon, F. Mougin, C. Bousquet, and A. Burgun, Evidence in pharmacovigilance : extracting Adverse Drug Reactions articles from MEDLINE to link them to case databases, Stud Health Technol Inform, vol.124, pp.528-533, 2006.

F. Mougin and O. Bodenreider, Approaches to eliminating cycles in the UMLS Metathesaurus : Naïve vs. formal, AMIA Annu Symp Proc, pp.550-554, 2005.

A. Burgun, O. Bodenreider, and F. Mougin, Classifying diseases with respect to anatomy : a study in SNOMED CT, AMIA Annu Symp Proc, 2005.

V. Bertaud, J. Lasbleiz, F. Mougin, F. Marin, A. Burgun et al., Toward a unified representation of findings in clinical radiology. Stud Health Technol Inform, vol.116, pp.671-677, 2005.

F. Mougin, A. Burgun, O. Loréal, L. Beux, and P. , Towards the automatic generation of biomedical sources schema, Medinfo, pp.783-787, 2004.

F. Mougin, M. Cuggia, and L. Beux, Development of an indexing search engine for the UMVF : Proposal for an indexing method based on Dublin Core and XML, Stud Health Technol Inform, vol.95, pp.727-731, 2003.

, Conférences nationales

F. Mougin, A. Burgun, and O. Bodenreider, Méthodes pour résoudre lhétérogénéité sémantique des « data elements » de sources de données biomédicales pour leur intégration, Workshop Ontologie, Grille et intégration Sémantique pour la Biologie (OGSB), JOBIM, 4 juillet 2006, Bordeaux Mougin F., Bodenreider O.Éliminer les cycles dans les systèmes terminologiques : comparaison de deux approches, 2006.

F. Mougin, C. Golbreich, A. Burgun, L. Beux, P. Rouen-mougin et al., Optimisation des Recherches Bibliographiques MedLine Pour le Non Expertà partir d'un Outil d'aideà la Navigation dans l'Indexation MeSH, Deuxième Journée Web Sémantique Médical, vol.9, pp.11-12, 2003.

F. Mougin, A. Burgun, and L. Beux, Les métadonnées dans le cadre du Web sémantique : applications au domaine biomédical, Première Journée Web Sémantique Médical, 17 mars, 2003.

F. Mougin, M. Cuggia, L. Duff, F. Kamendje, B. et al., Proposition de méthode pour l'indexation des ressources documentaires de l'UMVF, Internet et Pédagogie Médicale, 2002.

F. Posters-mougin, A. Burgun, O. Loréal, and L. Beux, UMLS-based approach to resolve biomedical sources heterogeneities, Actes de JOBIM 2005

F. Mougin, G. Marquet, A. Burgun, E. Guérin, and F. Moussouni, Use of metadata for biomedical heterogeneous data sources integration, Proceedings of the 2nd European Conference on Computational Biology, 2003.

. Gars||glycyl-trna-synthetase,

. Gba||glucosidase,

, GJB1||gap junction protein, vol.1, p.32

, HAMP||hepcidin antimicrobial peptide HBB||hemoglobin, beta

. Hd||huntingtin,

A. Hexa||hexosaminidase,

, HFE||hemochromatosis HMBS||hydroxymethylbilane synthase

. Hras||v-ha, ras Harvey rat sarcoma viral oncogene homolog KIF1B||kinesin family member 1B

, LITAF||lipopolysaccharide-induced TNF factor MPZ||myelin protein zero (Charcot-Marie-Tooth neuropathy 1B)

H. Nefh||neurofilament and . Polypeptide,

. Nefl||neurofilament, , p.68

, Watson disease) NF2||neurofibromin 2 (bilateral acoustic neuroma) PAH||phenylalanine hydroxylase PCBD||6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)

. Plod||procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI)

, PPOX||protoporphyrinogen oxidase PPP1R12A||protein phosphatase 1, regulatory (inhibitor) subunit 12A

T. Pten||phosphatase and . Homolog,

, QDPR||quinoid dihydropteridine reductase RAB7||RAB7, member RAS oncogene family RAD51||RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) RB1||Retinoblastoma, vol.1

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