Skip to Main content Skip to Navigation
Theses

Use of additive manufacturing techniques for the production of customized implants with complex geometry : application to reparative hand surgery

Abstract : Osteoarthritis is a pathology that causes the degeneration of joint surfaces. In the particular case of the trapezo-metacarpal joint, osteoarthritis irreversibly deforms the trapezium bone, causing loss of mobility and reduced grip strength coupled with pain at the base of the thumb. However, therapeutic solutions are not satisfactory with limited functional recovery resulting in a loss of quality of life for the patient. In the case of the hand, the personalization of implants seems to be relevant because of the great variability of the joint mechanical characteristics and the musculoskeletal specificities. This thesis work focuses on the methodology for creating a trapezio-metacarpal implant patient-matched, based on the potentialities of additive metal manufacturing technologies. More generally, it involves developing, analyzing and validating the steps involved in the manufacture of any complex geometric implant from medical imaging to implantation. The work initially focuses on identifying specific patient parameters in order to numerically "rejuvenate" the deformed bone in its pre-pathological stage to design the ideal implant and adapt the model to additive manufacturing (DfAM). Implant manufacturing and post-treatment are also studied from a biological (cytocompatibility, immune system response), mechanical (microstructure, friction property) and morphological (quantification of geometric deviations) point of view. The surgical implantation approach is addressed through various tests on cadavers to better integrate the benefits / risks for the patient. A study on the psychology of the patient suffering from rhizarthrosis and his expectations for a therapeutic solution concludes this manuscript. The results have led to 2 patents and the writing of 6 scientific articles.
Complete list of metadata

https://tel.archives-ouvertes.fr/tel-03201136
Contributor : Abes Star :  Contact
Submitted on : Saturday, April 17, 2021 - 7:59:09 PM
Last modification on : Tuesday, April 20, 2021 - 12:09:23 PM

File

These_UTC_Augustin_Lerebours.p...
Version validated by the jury (STAR)

Identifiers

  • HAL Id : tel-03201136, version 1

Collections

Citation

Augustin Lerebours. Use of additive manufacturing techniques for the production of customized implants with complex geometry : application to reparative hand surgery. Biomechanics [physics.med-ph]. Université de Technologie de Compiègne, 2019. English. ⟨NNT : 2019COMP2531⟩. ⟨tel-03201136⟩

Share

Metrics

Record views

176

Files downloads

12