This is a summary of the author's PhD thesis supervised by Laetitia Jourdan and El-Ghazali Talbi and defended on 8 December 2009 at the Université Lille 1. The thesis is written in French and is available from http://sites.google.com/site/arnaudliefooghe/. This work deals with the design, implementation and experimental analysis of metaheuristics for solving multiobjective optimisation problems, with a particular interest on hard and large combinatorial problems from the field of logistics. After focusing on a unified view of multiobjective metaheuristics, we propose new cooperative, adaptive and parallel approaches. The performance of these methods are experimented on a scheduling and a routing problem involving two or three objective functions. We finally discuss how to adapt such metaheuristics during the search process in order to handle uncertainty that may occur from many different sources.