Abstract: In this paper we briefly summarize the contents of Manzonetto's PhD thesis which concerns denotational semantics and equational/order theories of the pure untyped lambda-calculus. The main research achievements include: (i) a general construction of lambda-models from reflexive objects in (possibly non-well-pointed) categories; (ii) a Stone-style representation theorem for combinatory algebras; (iii) a proof that no effective lambda-model can have lambda-beta or lambda-beta-eta as its equational theory (this can be seen as a partial answer to an open problem introduced by Honsell-Ronchi Della Rocca in 1984).