Minimum information about a protein affinity reagent (MIAPAR).
Julie Bourbeillon
(1, 2)
,
Sandra Orchard
(3)
,
Itai Benhar
(4)
,
Carl Borrebaeck
(5)
,
Antoine de Daruvar
(1, 6, 2)
,
Stefan Dübel
(7)
,
Ronald Frank
(8)
,
Frank Gibson
(9)
,
David Gloriam
(3)
,
Niall Haslam
(10)
,
Tara Hiltker
(11)
,
Ian Humphrey-Smith
(12)
,
Michael Hust
(7)
,
David Juncker
(13)
,
Manfred Koegl
(14)
,
Zoltàn Konthur
(15)
,
Bernhard Korn
(14)
,
Sylvia Krobitsch
(15)
,
Serge Muyldermans
(16, 17)
,
Per-Ake Nygren
(18)
,
Sandrine Palcy
(2, 6)
,
Bojan Polic
(19)
,
Henry Rodriguez
(11)
,
Alan Sawyer
(20)
,
Martin Schlapshy
(21)
,
Michael Snyder
(22)
,
Oda Stoevesandt
(23)
,
Michael J Taussig
(23)
,
Markus Templin
(24)
,
Matthias Uhlen
(18)
,
Silvere van Der Maarel
(25)
,
Christer Wingren
(5)
,
Henning Hermjakob
(3)
,
David James Sherman
(1, 2)
1
LaBRI -
Laboratoire Bordelais de Recherche en Informatique
2 MAGNOME - Models and Algorithms for the Genome
3 EMBL-EBI - European Bioinformatics Institute [Hinxton]
4 Department of Molecular Microbiology and Biotechnology
5 Department of Immunotechnology
6 CBIB - Centre de Bioinformatique de Bordeaux
7 Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig]
8 Department of Chemical Biology
9 Institute for Cell and Molecular Biosciences
10 CASL - Complex & Adaptive Systems Laboratory - University College Dublin
11 NCI-NIH - National Cancer Institute [Bethesda]
12 Deomed Limited
13 BME - Department of Biomedical Engineering [Montréal]
14 DKFZ - German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg]
15 MPIMG - Max Planck Institute for Molecular Genetics
16 Laboratory of Cellular and Molecular Immunology
17 Department of Molecular and Cellular Interactions
18 KTH - KTH Royal Institute of Technology [Stockholm]
19 University of Rijeka
20 EMBL - European Molecular Biology Laboratory [Monterotondo]
21 TUM - Technische Universität Munchen - Technical University Munich - Université Technique de Munich
22 Department of Genetics [Stanford]
23 The Babraham Institute [Cambridge, UK]
24 University of Tübingen
25 Universiteit Leiden = Leiden University
2 MAGNOME - Models and Algorithms for the Genome
3 EMBL-EBI - European Bioinformatics Institute [Hinxton]
4 Department of Molecular Microbiology and Biotechnology
5 Department of Immunotechnology
6 CBIB - Centre de Bioinformatique de Bordeaux
7 Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig]
8 Department of Chemical Biology
9 Institute for Cell and Molecular Biosciences
10 CASL - Complex & Adaptive Systems Laboratory - University College Dublin
11 NCI-NIH - National Cancer Institute [Bethesda]
12 Deomed Limited
13 BME - Department of Biomedical Engineering [Montréal]
14 DKFZ - German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg]
15 MPIMG - Max Planck Institute for Molecular Genetics
16 Laboratory of Cellular and Molecular Immunology
17 Department of Molecular and Cellular Interactions
18 KTH - KTH Royal Institute of Technology [Stockholm]
19 University of Rijeka
20 EMBL - European Molecular Biology Laboratory [Monterotondo]
21 TUM - Technische Universität Munchen - Technical University Munich - Université Technique de Munich
22 Department of Genetics [Stanford]
23 The Babraham Institute [Cambridge, UK]
24 University of Tübingen
25 Universiteit Leiden = Leiden University
Julie Bourbeillon
- Function : Author
- PersonId : 5742
- IdHAL : julie-bourbeillon
- ORCID : 0000-0002-3365-1286
- IdRef : 125302290
Henning Hermjakob
- Function : Author
- PersonId : 760092
- ORCID : 0000-0001-8479-0262
David James Sherman
- Function : Author
- PersonId : 1356
- IdHAL : david-james-sherman
- ORCID : 0000-0002-2316-1005
- IdRef : 09147101X
Abstract
This is a proposal developed within the community as an important first step in formalizing standards in reporting the production and properties of protein binding reagents, such as antibodies, developed and sold for the identification and detection of specific proteins present in biological samples. It defines a checklist of required information, intended for use by producers of affinity reagents, quality-control laboratories, users and databases. We envision that both commercial and freely available affinity reagents, as well as published studies using these reagents, could include a MIAPAR-compliant document describing the product's properties with every available binding partner.