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Conference papers

Hybrid models for the interconnection of circadian and genetic cycles in cyanobacteria

Madalena Chaves 1 Miguel Preto 2
1 BIOCORE - Biological control of artificial ecosystems
INRA - Institut National de la Recherche Agronomique, CRISAM - Inria Sophia Antipolis - Méditerranée , LOV - Laboratoire d'océanographie de Villefranche
Abstract : This paper will discuss the coupling of two oscillators in cyanobacteria. The circadian rhythm of cyanobacteria is thought to be driven by an oscillator based on an ordered sequence of phosphorylations of a protein (KaiC). At the same time, as the cyanobacterial cell grows and divides, the amount of protein KaiC itself is regulated by a transcription/ translation cycle. Our goals are to study: (i) the robustness of the circadian rhythm with respect to the perturbations inherent to the noisy environment of the cell, including cell growth and division; and (ii) to what extent the growth curves of cyanobacterial colonies, under different external light conditions, are modulated by the circadian cycle.
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Contributor : Jean-Luc Gouzé <>
Submitted on : Monday, December 15, 2014 - 11:49:48 AM
Last modification on : Tuesday, March 17, 2020 - 3:18:43 AM


  • HAL Id : hal-01095211, version 1


Madalena Chaves, Miguel Preto. Hybrid models for the interconnection of circadian and genetic cycles in cyanobacteria. 21st International Symposium on Mathematical Theory of Networks and Systems, Jul 2014, Groningen, Netherlands. pp.4. ⟨hal-01095211⟩