System and method for personalized computation of tissue ablation extent based on medical images

Abstract : A method and system for personalized computation of tissue ablation extent based on medical images of a patient is disclosed. A patient-specific anatomical model of the liver and liver vessels is estimated from medical image data of a patient. Blood flow in the liver and liver vessels is simulated. An ablation simulation is performed that uses a bio-heat model to simulate heat diffusion due to an ablation based on the simulated blood flow and a cellular necrosis model to simulate cellular necrosis in the liver based on the simulated heat diffusion. Personalized tissue parameters of the bio-heat model and the cellular necrosis model are estimated based on observed results of a preliminary ablation procedure. Planning of the ablation procedure is then performed using the personalized bio-heat equation and the cellular necrosis model. The model can be subsequently refined as more ablation observations are obtained.
Type de document :
Brevet
United States, Patent n° : US 2015/0242588 A1. 2015
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https://hal.inria.fr/hal-01253687
Contributeur : Project-Team Asclepios <>
Soumis le : lundi 11 janvier 2016 - 11:29:19
Dernière modification le : jeudi 11 janvier 2018 - 16:48:47

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  • HAL Id : hal-01253687, version 1

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Chloé Audigier, Tommaso Mansi, Saikiran Rapaka, Ali Kamen, Viorel Mihalef, et al.. System and method for personalized computation of tissue ablation extent based on medical images. United States, Patent n° : US 2015/0242588 A1. 2015. 〈hal-01253687〉

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