OFSEP, a nationwide cohort of people with multiple sclerosis: Consensus minimal MRI protocol

Roxana Amélie 1 René Anxionnat 2 Jean-Paul Armspach 3 Bertrand Audoin 4, 5 Christian Barillot 6 Isabelle Berry 7 Fabrice Bonneville 8 Claire Boutet 9, 10, 11, 12 Giovanni Castelnovo 13 Frédéric Cervenanski 14 Mikael Cohen 15 Olivier Commowick 6 François Cotton 14 Jérôme De Seze 1 Vincent Dousset 16 Françoise Durand-Dubief 14 Gilles Edan 6, 17 Jean-Christophe Ferre 6, 18, 19 Damien Galanaud 20, 9, 12 Tristan Glattard 14 Sylvie Grand 21 Justine Guillaumont 6 Rémy Guillevin 22 Charles Guttmann 23 Salem Hannoun 14 Fabrice Heitz 24 Alexandre Krainik 25, 26 Stéphane Kremer 27 Pierre Labauge 4 Nicolas Menjot de Champfleur 28 Jean-Philippe Ranjeva 4 Jean-Amédée Roch 29 Dominique Sappey-Marinier 30 Julien Savatovsky 31 Bruno Stankoff 32, 33, 9 Thomas Tourdias 16 Ayman Tourbah 34 Sandra Vukusic 35
2 ISA - Models, algorithms and geometry for computer graphics and vision
INRIA Lorraine, LORIA - Laboratoire Lorrain de Recherche en Informatique et ses Applications
6 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
12 ARAMIS - Algorithms, models and methods for images and signals of the human brain
UPMC - Université Pierre et Marie Curie - Paris 6, ICM - Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute, Inria de Paris
Abstract : Multiple sclerosis (MS) is most generally considered as a severe disease with high physical and mental risks of disability. Since the end of the 1990s, several high cost long-term disease-modifying treatments provided some clinical efficiency. However, patient's follow-up was needed for the detection and the assessment of their side-effects. The “Observatoire français de la sclérose en plaques” (OFSEP) project aims to improve the clinical, biological and imaging systematic longitudinal follow-up of patients. It should increase the quality, efficiency and safety of patients’ care, with a unique opportunity of large scale, about 41,000 patients followed in 62 French centers using the European Database for Multiple Sclerosis (EDMUS) software. OFSEP is divided into three working groups (clinical, biological and imaging). The imaging working group defines standards for routine MRI follow-up in the whole cohort and contains three subgroups: acquisition, workflow, and data processing. A common and feasible brain and spinal cord acquisition protocol has been defined by the acquisition group, and accepted by the OFSEP steering and scientific committees. This protocol can be implemented in all French MRI centers. The major MRI manufacturers have agreed to provide the dedicated collection of sequences as an “OFSEP box” with every software upgrade or new MRI machine. The new OFSEP protocol will provide a unique opportunity to study a population-based collection of data from people with MS.
Type de document :
Article dans une revue
Journal de Neuroradiologie / Journal of Neuroradiology, Elsevier Masson, 2015, 42 (3), pp.133 - 140. 〈10.1016/j.neurad.2014.12.001〉
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https://hal.inria.fr/hal-01378309
Contributeur : Jean-Christophe Ferré <>
Soumis le : dimanche 9 octobre 2016 - 21:39:20
Dernière modification le : dimanche 15 octobre 2017 - 22:44:04

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Roxana Amélie, René Anxionnat, Jean-Paul Armspach, Bertrand Audoin, Christian Barillot, et al.. OFSEP, a nationwide cohort of people with multiple sclerosis: Consensus minimal MRI protocol. Journal de Neuroradiologie / Journal of Neuroradiology, Elsevier Masson, 2015, 42 (3), pp.133 - 140. 〈10.1016/j.neurad.2014.12.001〉. 〈hal-01378309〉

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