Data for the qualitative modeling of the osmotic stress response to NaCl in Escherichia coli

Delphine Ropers 1 Aline Métris 2
1 IBIS - Modeling, simulation, measurement, and control of bacterial regulatory networks
LAPM - Laboratoire Adaptation et pathogénie des micro-organismes [Grenoble], Inria Grenoble - Rhône-Alpes, Institut Jean Roget
Abstract : Qualitative modeling approaches allow to provide a coarse-grained description of the functioning of cellular networks when experimental data are scarce and heterogeneous. We translate the primary literature data on the response of Escherichia coli to hyperosmotic stress caused by NaCl addition into a piecewise linear (PL) model. We provide a data file of the qualitative model, which can be used for simulation of changes of protein concentrations and of DNA coiling during the physiological response of the bacterium to the stress. The qualitative model predictions are directly comparable to the available experimental data. This data is related to the research article entitled “Piecewise linear approximations to model the dynamics of adaptation to osmotic stress by food-borne pathogens” (Metris et al., 2016).
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https://hal.inria.fr/hal-01417966
Contributeur : Delphine Ropers <>
Soumis le : vendredi 16 décembre 2016 - 11:23:45
Dernière modification le : jeudi 7 juin 2018 - 17:50:03

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Delphine Ropers, Aline Métris. Data for the qualitative modeling of the osmotic stress response to NaCl in Escherichia coli. Data in Brief, Elsevier, 2016, 9, pp.606-612. 〈http://www.sciencedirect.com/science/article/pii/S235234091630600X〉. 〈10.1016/j.dib.2016.09.028〉. 〈hal-01417966〉

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