Introduction: Improving swimming performance involves assessments of biomechanical variables of the stroke, and it can be achieved using semi-tethered swimming tests. The aim of this study was thus to investigate the associations between load-velocity (L-V) profiles, from a semi-tethered swimming protocol and race variables in the 100 m and 200 m freestyle events. Methods: Eight swimmers completed a L-V profiling protocol consisting of four sprints (25 m, 25 m, 20 m, 15 m) against increasing loads (0.1, 2.0, 4.0, 6.0 kg respectively) with complete recovery between repetitions (>5 min). The L-V linear regression was used to estimate maximal velocity (V0) and body mass normalized load (rL0). Race variables such as clean swimming speed (V), stroke rate (SR), distance per cycle (SL) and stroke index (SI) were assessed from video analysis of 100 m and 200 m freestyle events taking place 3–4 days after the L-V protocol. Results: L-V results showed high levels of speed (mean ± SD: 1.87 ± 0.04 m/s) and heavy maximal relative loads (mean ± SD: 38.5 ± 6.51 as % of body mass). Swimmers also achieved high-level performances in the 100 m (mean ± SD time: 51.95 ± 0.75 s) and the 200 m (mean ± SD time: 113.85 ± 2.67 s). For the 100 m events, the maximal relative load showed strong correlation with performance (r = 0.63) whereas trivial correlation was observed for the 200 m events (r = 0.12). SR on the 100 m and the 200 m also showed very strong association with rL0 (r = 0.83) and a strong association with V0 (r = 0.68) respectively. Conclusion: The relationships between L-V variables and race variables depend on the distance of the event. However, L-V variables seem to be less related to SR and SL evolutions for the 100 m than in the 200 m event. Moreover, L-V profiles tend to be more related to the 100 m than 200 m freestyle performance. L-V profile should be interpreted taking into consideration the specific physiological and biomechanical constraints of the main events of the swimmer.