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Conference papers

Biophysical cortical column model for optical signal analysis

Sandrine Chemla 1 Thierry Viéville 2 Frederic Chavane 3
1 ODYSSEE - Computer and biological vision
DI-ENS - Département d'informatique de l'École normale supérieure, CRISAM - Inria Sophia Antipolis - Méditerranée , ENS Paris - École normale supérieure - Paris, Inria Paris-Rocquencourt, ENPC - École des Ponts ParisTech
2 CORTEX - Neuromimetic intelligence
INRIA Lorraine, LORIA - Laboratoire Lorrain de Recherche en Informatique et ses Applications
Abstract : We propose a biological cortical column model, at a some mesoscopic scale, in order to better understand and start to interpret biological sources of voltagesensitive dye imaging signal. The mesoscopic scale, corresponding to a micro-column, is about 50 ,m. Simulations are done thanks to the NEURON and NEURONCONSTRUCT software. This model suggests that the OI signal is the result of an average from multiple components whose proportion changes with levels of activity and shows surprisingly that inhibitory cells, spiking activity and deep layers may well participate more to the signal than initially though.
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Contributor : Thierry Viéville <>
Submitted on : Wednesday, November 12, 2008 - 10:53:05 PM
Last modification on : Saturday, October 3, 2020 - 3:18:48 AM


  • HAL Id : inria-00338370, version 1


Sandrine Chemla, Thierry Viéville, Frederic Chavane. Biophysical cortical column model for optical signal analysis. AREADNE Research in Encoding and Decoding of Neural Ensembles, Jun 2008, Santorini, Greece. ⟨inria-00338370⟩



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