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Journal Articles Nonlinear Analysis: Real World Applications Year : 2005

Existence, positivity and stability for a nonlinear model of cellular proliferation

Abstract

In this paper, we investigate a system of two nonlinear partial differential equations, arising from a model of cellular proliferation which describes the production of blood cells in the bone marrow. Due to cellular replication, the two partial differential equations exhibit a retardation of the maturation variable and a temporal delay depending on this maturity. We show that this model has a unique solution which is global under a classical Lipschitz condition. We also obtain the positivity of the solutions and the local and global stability of the trivial equilibrium.
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Dates and versions

hal-00375934 , version 1 (16-04-2009)

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Mostafa Adimy, Fabien Crauste. Existence, positivity and stability for a nonlinear model of cellular proliferation. Nonlinear Analysis: Real World Applications, 2005, 6 (2), pp.337-366. ⟨10.1016/j.nonrwa.2004.09.001⟩. ⟨hal-00375934⟩
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