HAL - INRIA :: [inria-00178854, version 1] Qualitative response of interaction networks: application to the validation of biological models

inria-00178854, version 1

Qualitative response of interaction networks: application to the validation of biological models

Anne Siegel ( Auteur à contacter de préférence ) ¹, Carito Guziolowski ()^a^, 1, Philippe Veber^b^, 1, Ovidiu Radulescu ()^c^, 1, 2, Michel Le Borgne ()^c^, 1

6th International Congress on Industrial and Applied Mathematics. ICIAM 07 (2007) nc

Résumé : We advocate the use of qualitative models for the analysis of shift equilibria in large biological systems. We present a mathematical method, allowing qualitative predictions to be made of the behaviour of a biological system. These predictions are not dependent on specific values of the kinetic constants. We show how these methods can be used to improve understanding of a complex regulatory system.

a – Comisión Nacional de Investigación en Ciencia y Tecnología
b – INRIA
c – Université Rennes I
1 : SYMBIOSE (INRIA - IRISA)
CNRS : UMR6074 – INRIA – INSA Rennes – Université de Rennes 1
2 : Institut de Recherche Mathématique de Rennes (IRMAR)
CNRS : UMR6625 – Université de Rennes 1 – École normale supérieure de Cachan - ENS Cachan – INSA Rennes – Université Rennes II

inria-00178854, version 1
http://hal.inria.fr/inria-00178854
oai:hal.inria.fr:inria-00178854
Contributeur : Anne Siegel <>
Soumis le : Vendredi 12 Octobre 2007, 12:52:09
Dernière modification le : Mercredi 24 Mars 2010, 09:39:17

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