This paper deals with on-line identification of continuous-time systems with structured entries. Such entries, which may consist in inputs, perturbations or piecewise polynomial (time varying) parameters, can be defined as signals that can be easily annihilated. The proposed cancellation method allows to obtain non asymptotic estimators for the unknown coefficients. Application to delayed and switching hybrid systems are proposed. Numerical simulations with noisy data but also experimental results on a delay process are provided.