Glioblastoma growth modeling for radiotherapy target delineation.

Abstract : Radiotherapy treatment planning requires a localization of the tumor within the patient. This is challenging to accomplish for micro- scopic in ltrative spread of disease that is not visible on current imaging modalities. Prime examples for in ltrative tumors are gliomas. With the help of mathematical models, common growth characteristics of gliomas, which are known from histopathological studies, can be incorporated in radiotherapy target delineation. This requires an imaging based personal- ization of the model to the individual patient. We demonstrate use cases of the Fisher-Kolmogorov glioma growth model in radiotherapy planning of a clinical case. We further analyze the crucial input parameters to the model, in particular, the need for reliable segmentation of anatomical boundaries such as the falx cerebri and the tentorium cerebelli.
Type de document :
Communication dans un congrès
Wolfgang Birkfellner and Jamie R. Mcclelland and Simon Rit and Alexander Schlaefer. Image-Guidance and Multimodal Dose Planning in Radiation Therapy, 2012, Nice, France. pp.9-16, 2012, Proceedings of the first MICCAI workshop on Image-Guidance and Multimodal Dose Planning in Radiation Therapy
Liste complète des métadonnées

https://hal.inria.fr/hal-00813872
Contributeur : Project-Team Asclepios <>
Soumis le : mardi 16 avril 2013 - 11:21:20
Dernière modification le : jeudi 11 janvier 2018 - 16:41:49

Identifiants

  • HAL Id : hal-00813872, version 1

Collections

Citation

J. Unkelbach, Bjoern H. Menze, A. Motamedi, F. Dittmann, Ender Konukoglu, et al.. Glioblastoma growth modeling for radiotherapy target delineation.. Wolfgang Birkfellner and Jamie R. Mcclelland and Simon Rit and Alexander Schlaefer. Image-Guidance and Multimodal Dose Planning in Radiation Therapy, 2012, Nice, France. pp.9-16, 2012, Proceedings of the first MICCAI workshop on Image-Guidance and Multimodal Dose Planning in Radiation Therapy. 〈hal-00813872〉

Partager

Métriques

Consultations de la notice

192