This Communication seeks to propose a theoretical framework for the emerging concept of "acadepreneurship". In fact, we try to to implement an entrepreneurial logic within the University. The aims of this contribution is to try to advance an epistemological and theoretical framework of entrepreneurship via a multiparadigmatic reading of the phenomenon. This article focuses on two main issues. the first seeks to clarify the epistemological position of entrepreneurship research and the transcription of the entrepreneurial paradigm in university. The second seeks to build a scoping of the neologism of acadepreneurship and to distinguish it from the concept of academic entrepreneurship.