Modeling the emergence of stage II retinal waves in immature retina

Abstract : Retinal waves are spontaneous bursting activity propagating in the developping retina until vision is functional. In this work we propose a biophysical modelling of the mechanism that generates the spontaneous intrinsic cell-autonomous rhythmic bursting in Starbust Amacrine Cells (SACs), observed experimentally in [1] which is directly linked with the emergence of stage II retinal waves. We analyze this system from the dynamical system and bifurcation theory perspective.
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Dora Karvouniari, Lionel Gil, Olivier Marre, Serge Picaud, Bruno Cessac. Modeling the emergence of stage II retinal waves in immature retina. AREADNE 2016 Research in Encoding And Decoding of Neural Ensembles, Jun 2016, Santorini, Greece. ⟨hal-01339875⟩

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