OPTIMAL PLACEMENT OF ELECTRODES IN AN ELECTROPORATION PROCESS

Abstract : Electroporation consists in increasing the permeability of a tissue by applying high voltage pulses. In this paper we discuss the question of optimal placement and optimal loading of electrodes such that electroporation holds only in a given open set of the domain. The electroporated set of the domain is where the norm of the electric field is above a given threshold value. We use a standard gradient algorithm to optimize the loading of the electrodes and shape sensitivity analysis and a gradient algorithm in order to move the electrodes. We also discuss the choice of objective functions to be chosen in the gradient algorithm.
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ESAIM: Proceedings, EDP Sciences, 2010, 30, pp.34-43. 〈10.1051/proc/2010004〉
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Contributeur : Clair Poignard <>
Soumis le : jeudi 9 décembre 2010 - 10:41:36
Dernière modification le : jeudi 11 janvier 2018 - 06:25:42

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Nicolae Cindea, Benoît Fabrèges, Frédéric De Gournay, Clair Poignard. OPTIMAL PLACEMENT OF ELECTRODES IN AN ELECTROPORATION PROCESS. ESAIM: Proceedings, EDP Sciences, 2010, 30, pp.34-43. 〈10.1051/proc/2010004〉. 〈inria-00544874〉

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