Computation of the Mid-Sagittal Plane in 3D Brain Images

Sylvain Prima 1, * Sébastien Ourselin 1 Nicholas Ayache 1, *
* Auteur correspondant
1 EPIDAURE - Medical imaging and robotics
CRISAM - Inria Sophia Antipolis - Méditerranée
Abstract : We present a new method to automatically compute, reorient, and recenter the mid-sagittal plane in anatomical and functional three-dimensional (3-D) brain images. This iterative approach is composed of two steps. At first, given an initial guess of the mid-sagittal plane (generally, the central plane of the image grid), the computation of local similarity measures between the two sides of the head allows to identify homologous anatomical structures or functional areas, by way of a block matching procedure. The output is a set of point-to-point correspondences: the centers of homologous blocks. Subsequently, we define the mid-sagittal plane as the one best superposing the points on one side and their counterparts on the other side by reflective symmetry. Practically, the computation of the parameters characterizing the plane is performed by a least trimmed squares estimation. Then, the estimated plane is aligned with the center of the image grid, and the whole process is iterated until convergence. The robust estimation technique we use allows normal or abnormal asymmetrical structures or areas to be treated as outliers, and the plane to be mainly computed from the underlying gross symmetry of the brain. The algorithm is fast and accurate, even for strongly tilted heads, and even in presence of high acquisition noise and bias field, as shown on a large set of synthetic data. The algorithm has also been visually evaluated on a large set of real magnetic resonance (MR) images.We present a few results on isotropic as well as anisotropic anatomical (MR and computed tomography) and functional (single photon emission computed tomography and positron emission tomography) real images, for normal and pathological subjects.
Type de document :
Article dans une revue
IEEE Transactions on Medical Imaging, Institute of Electrical and Electronics Engineers, 2002, 21 (2), pp.122-138. 〈10.1109/42.993131〉
Liste complète des métadonnées
Contributeur : Project-Team Asclepios <>
Soumis le : mercredi 17 août 2011 - 23:15:44
Dernière modification le : samedi 27 janvier 2018 - 01:32:20
Document(s) archivé(s) le : vendredi 25 novembre 2011 - 11:26:19

Fichiers produits par l'(les) auteur(s)




Sylvain Prima, Sébastien Ourselin, Nicholas Ayache. Computation of the Mid-Sagittal Plane in 3D Brain Images. IEEE Transactions on Medical Imaging, Institute of Electrical and Electronics Engineers, 2002, 21 (2), pp.122-138. 〈10.1109/42.993131〉. 〈inria-00615027〉



Consultations de la notice


Téléchargements de fichiers