VT Scan: Towards an Efficient Pipeline from Computed Tomography Images to Ventricular Tachycardia Ablation

Nicolas Cedilnik 1, 2 Josselin Duchateau 3 Rémi Dubois 3 Pierre Jaïs 3 Hubert Cochet 3 Maxime Sermesant 1, 2
1 UCA - Université Côte d'Azur
2 ASCLEPIOS - Analysis and Simulation of Biomedical Images
CRISAM - Inria Sophia Antipolis - Méditerranée
3 IHU-LIRYC
Abstract : Non-invasive prediction of optimal targets for efficient radio-frequency ablation is a major challenge in the treatment of ventricular tachycardia. Most of the related modelling work relies on magnetic resonance imaging of the heart for patient-specific personalized electrophysiology simulations. In this study, we used high-resolution computed tomography images to personalize an Eikonal model of cardiac electrophysiology in seven patients, addressed to us for catheter ablation in the context of post-infarction arrhythmia. We took advantage of the detailed geometry offered by such images, which are also more easily available in clinical practice, to estimate a conduction speed parameter based on myocardial wall thickness. We used this model to simulate a propagation directly on voxel data, in similar conditions to the ones invasively observed during the ablation procedure. We then compared the results of our simulations to dense activation maps that recorded ventricular tachycardias during the procedures. We showed as a proof of concept that realistic re-entrant pathways responsible for ventricular tachycardia can be reproduced using our framework, directly from imaging data.
Keywords : Catheter ablation Ventricular tachycardia Heart imaging Electrophysiological modelling
Type de document :
Communication dans un congrès
Functional Imaging and Modelling of the Heart, Jun 2017, Toronto, Canada. Springer International Publishing, pp.271-279, 2017, Functional Imaging and Modelling of the Heart. 〈https://fimh2017.joomla.com/〉. 〈10.1007/978-3-319-59448-4_26〉
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Soumis le : lundi 3 avril 2017 - 10:00:43
Dernière modification le : jeudi 11 janvier 2018 - 16:49:58

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Nicolas Cedilnik, Josselin Duchateau, Rémi Dubois, Pierre Jaïs, Hubert Cochet, et al.. VT Scan: Towards an Efficient Pipeline from Computed Tomography Images to Ventricular Tachycardia Ablation. Functional Imaging and Modelling of the Heart, Jun 2017, Toronto, Canada. Springer International Publishing, pp.271-279, 2017, Functional Imaging and Modelling of the Heart. 〈https://fimh2017.joomla.com/〉. 〈10.1007/978-3-319-59448-4_26〉. 〈hal-01498672v2〉

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